A brief review of influenza virus infection

Mostafa Javanian, Mohammad Barary, Samuel Ghebrehewet, Veerendra Koppolu, Veneela Krishna Rekha Vasigala, Soheil Ebrahimpour

    Research output: Contribution to journalReview articlepeer-review


    Influenza is an acute viral respiratory infection that affects all age groups and is associated with high mortality during pandemics, epidemics, and sporadic outbreaks. Nearly 10% of the world's population is affected by influenza annually, with about half a million deaths each year. Influenza vaccination is the most effective method for preventing influenza infection and its complications. The influenza vaccine's efficacy varies each season based on the circulating influenza strains and vaccine uptake rates. Currently, three antiviral drugs targeting the influenza virus surface glycoprotein neuraminidase are available for treatment and prophylaxis of disease. Given the significant burden of influenza infection globally, this review is focused on the latest findings in the etiology, epidemiology, transmission, clinical manifestation, diagnosis, prevention, and treatment of influenza.

    Original languageEnglish
    Pages (from-to)4638-4646
    Number of pages9
    JournalJournal of Medical Virology
    Issue number8
    Publication statusAccepted/In press - 2021


    • antiviral agents
    • epidemiology
    • influenza virus, treatment


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