A case-control study of elderly patients with acute respiratory illness: Effect of influenza vaccination on admission to hospital in winter 2003-2004

R. E. Jordan, Jeremy Hawker, J. G. Ayres, W. Tunnicliffe, P. Adab, Babatunde Olowokure, J. Kai, R. J. McManus, R. Salter, K. K. Cheng

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9 Citations (Scopus)

Abstract

Every winter, hospitals face a large increase in emergency respiratory admissions in elderly people. A case-control study was undertaken to assess the effect of routine influenza vaccine in preventing such admissions among a cohort of UK elderly presenting with acute respiratory illness during winter 2003-2004. 157 hospitalised cases and 639 controls (matched for age, sex and week of consultation) were interviewed. In a winter typical of levels of circulating influenza in recent years, influenza vaccine did not show a protective effect on emergency respiratory admissions overall (adjusted OR 1.2 (95%CI 0.8, 1.9). Policy makers should not rely solely on influenza vaccine routinely having a large effect on winter pressures, and should focus on additional preventive strategies.

Original languageEnglish
Pages (from-to)7909-7913
Number of pages5
JournalVaccine
Volume25
Issue number46
DOIs
Publication statusPublished - 14 Nov 2007

Keywords

  • Elderly
  • Influenza vaccine
  • Winter hospital admissions

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