A new cytogenetic biodosimetry image repository for the dicentric assay

Horst Romm*, Christina Beinke, Omar Garcia, Marina Di Giorgio, Eric Gregoire, Gordon Livingston, David C. Lloyd, Wilner Martìnez-Lopez, Jayne Moquet, Stephen L. Sugarman, Ruth C. Wilkins, Elizabeth Ainsbury

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The BioDoseNet was founded by the World Health Organization as a global network of biodosimetry laboratories for building biodosimetry laboratory capacities in countries. The newly established BioDoseNet image repository is a databank of ~25 000 electronically captured images of metaphases from the dicentric assay, which have been previously analysed by international experts. The detailed scoring results and dose estimations have, in most cases, already been published. The compilation of these images into one image repository provides a valuable tool for training and research purposes in biological dosimetry. No special software is needed to view and score the image galleries. For those new to the dicentric assay, the BioDoseNet Image Repository provides an introduction to and training for the dicentric assay. It is an excellent instrument for intra-laboratory training purposes or inter-comparisons between laboratories, as recommended by the International Organization for Standardisation standards. In the event of a radiation accident, the repository can also increase the surge capacity and reduce the turnaround time for dose estimations. Finally, it provides a mechanism for the discussion of scoring discrepancies in difficult cases.

Original languageEnglish
Pages (from-to)192-200
Number of pages9
JournalRadiation Protection Dosimetry
Volume172
Issue number1-3
DOIs
Publication statusPublished - Dec 2016

Bibliographical note

Publisher Copyright:
© The Author 2016.

Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.

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