An outbreak of human listeriosis associated with frozen sweet corn consumption: Investigations in the UK

James McLauchlin*, Heather Aird, Corinne Amar, Clare Barker, Tim Dallman, Sandra Lai, Anais Painset, Caroline Willis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The use of Whole genome sequencing (WGS) identified a multi-country outbreak of human listeriosis associated with consumption of frozen sweet corn produced in Hungary. The purpose of this report was to summarise information on the cases occurring in the UK which were part of this outbreak and outline investigations on the presence of Listeria monocytogenes in the affected food chain. Prior to the international recall of this product in 2018, 12 UK cases of listeriosis were identified as infected by the outbreak strain between 2015 and 18. Epidemiological and microbiological investigations confirmed these cases as belonging to the outbreak. A further case occurred in 2019 and a contaminated frozen pack from one of the implicated batches of sweet corn was recovered from the patient's domestic freezer. The outbreak strain was also detected in products from a sandwich manufacturer in 2018 which added frozen sweet corn directly to sandwich fillings. The sandwich manufacturer's sweet corn was supplied by a distributor in England which obtained frozen products from the Hungarian manufacturer implicated in the outbreak. Within the distributor's premises, 208 food and environmental samples were taken: L. monocytogenes was detected in 44% of 70 samples of frozen sweet corn and 5% of 79 other foods. The outbreak strain was detected in the frozen sweet corn, in one other frozen food (mixed vegetables) and in the factory environment. The outbreak strain was also recovered from frozen beans on retail sale in the first four months of 2019. Five other L. monocytogenes strains together with two other Listeria species were detected in samples from the importer's premises. One of the L. monocytogenes strains in the importer's factory, which was distinct from the outbreak strain, was also recovered from sweet corn collected from the sandwich manufacturer, sweet corn tested in England in 2013 and 2016 and the blood of two cases of human listeriosis which occurred in England in 2014. This report shows how analysis by WGS provides evidence to understand complex food chains. This report also highlights risks for transmission of human listeriosis from frozen sweet corn and the potential for misuse of this food as a ready-to-eat product.

Original languageEnglish
Article number108994
Number of pages9
JournalInternational Journal of Food Microbiology
Volume338
DOIs
Publication statusPublished - 2 Jan 2021

Bibliographical note

Funding Information:
The authors would also like to thank members of the multiagency Outbreak Control Team for their valuable contribution in investigating the outbreak. We would also like to thanks J Gregory, M Easton, A Goncalves Da Silva, D Williamson and S Ballard of the The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia for details of the case in Australia. CB, TD and AP are affiliated to the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Gastrointestinal Infections at University of Liverpool in partnership with Public Health England (PHE), in collaboration with University of East Anglia, University of Oxford and the Quadram Institute. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, the Department of Health and Social Care or Public Health England. This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors.

Keywords

  • Food and environmental surveillance
  • Food safety
  • Foodborne infection
  • Listeria monocytogenes
  • Sweet corn
  • Whole genome sequencing
  • MONOCYTOGENES
  • PERSISTENCE
  • TOOL

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