An outbreak of Shiga toxin-producing Escherichia coli serogroup O157 linked to a lamb-feeding event

S. Rowell, C. King, Claire Jenkins, Tim Dallman, V. Decraene, K. Lamden, A. Howard, C. A. Featherstone, Paul Cleary

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Fifteen confirmed cases and 15 possible cases of Shiga toxin-producing Escherichia coli (STEC) O157 phage type 21/28 were linked to direct contact with lambs at a 'Lambing Live' event in the North West of England between 29 March and 21 April 2014. Twenty-one (70%) of the cases were female, 23 (77%) were children aged <16 years, of whom 14 (46%) were in the 0-5 years age group. Five children developed haemolytic uraemic syndrome. Multilocus variable number tandem repeat analysis (MLVA) profiles on 14 human cases were indistinguishable, and 6/10 animal isolates had a MLVA profile identical to the outbreak profile. Whole-genome sequencing analysis revealed that all isolates, both human and animal, fell within a 5-single nucleotide polymorphism cluster indicating the isolates belonged to the same point source. On inspection of the premises, extensive and uncontrolled physical contact between visitors and animals was occuring within the animal pens and during bottle-feeding. Public areas were visibly contaminated with animal faeces. Information to visitors, and the infection control awareness demonstrated by staff, was inadequate. Managing the risk to visitors of STEC O157 infection at animal petting events and open farms requires implementation of stringent control measures by the operator, as outlined in the industry code of practice. Enforcement action is sometimes required to prevent high-risk activities taking place at both permanent and temporary attractions.

Original languageEnglish
Pages (from-to)2494-2500
Number of pages7
JournalEpidemiology and Infection
Volume144
Issue number12
DOIs
Publication statusPublished - 1 Sep 2016

Keywords

  • Gastrointestinal infections
  • public health microbiology
  • Shiga-like toxin-producing E. coli
  • veterinary epidemiology and bacteriology

Fingerprint

Dive into the research topics of 'An outbreak of Shiga toxin-producing Escherichia coli serogroup O157 linked to a lamb-feeding event'. Together they form a unique fingerprint.

Cite this