An outbreak of shigella boydii serotype 20 in january 2015 amongst United Kingdom healthcare workers involved in the Ebola response in Sierra Leone

Daniel Todkill, Rachel Pudney, Andrew Terrell, Jerry Tuck, Emma Hutley, Tim Dallman, Claire Jenkins*, Rohini Manuel, Michael Wade, Richard Puleston, Jeremy Hawker

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In January 2015, Public Health England and the United Kingdom (UK) Ministry of Defence investigated cases of diarrhoea and fever in military personnel recently returned to the UK after supporting the response to the Ebola epidemic in Sierra Leone. Tests for Ebola virus infection were negative. PCR tests detected the ipaH gene in 10/12 faecal specimens, and Shigella boydii serotype 20 was isolated from 7 patients. A case control study was undertaken and analysed using multivariable logistic regression. Consumption of a coronation chicken lunch at the transit camp in Sierra Leone (SL) 24-48 h prior to departure for the UK was significantly associated with disease [adjusted odds ratio (OR) 28.15, 95%CI: 1.87-422.65]. In the context of heightened concern during the Ebola epidemic, this outbreak highlights the importance of rapid and effective microbiological and epidemiological investigations to identify the aetiological agent in patients presenting with fever and diarrhoea.

Original languageEnglish
Pages (from-to)1596-1600
Number of pages5
JournalJournal of Medical Microbiology
Volume67
Issue number11
DOIs
Publication statusPublished - Nov 2018

Bibliographical note

Funding Information:
T. D. and J. H. are affiliated to the National Institute for Health Research Health Protection Research Unit in Gastrointestinal Infections at University of Liverpool in partnership with Public Health England. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, the Department of Health or Public Health England.

Publisher Copyright:
© 2018 The Authors.

Keywords

  • Diarrhoea
  • Fever
  • Foodborne gastrointestinal disease
  • Outbreak
  • Shigella boydii

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