Analysis of recombination in Campylobacter jejuni from MLST population data

Paul Fearnhead, Nick G.C. Smith, Mishele Barrigas, Andrew Fox, Nigel French

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

We analyze recombination in C. jejuni using MLST data from isolates taken from wild birds, cattle, wild rabbits, and water in a 100-km2 study region in Cheshire, UK. We use a recent approximate likelihood method for inference, based on combining likelihood information from all pairs of segregating (polymorphic) sites in the data. We find substantial evidence for recombination, but only for recombination with short tract lengths, of around 225-750 bp. We estimate that the rate of recombination is of a similar magnitude to the rate of mutation.

Original languageEnglish
Pages (from-to)333-340
Number of pages8
JournalJournal of Molecular Evolution
Volume61
Issue number3
DOIs
Publication statusPublished - Sep 2005

Keywords

  • Bacteria
  • Campylobacter
  • Helicobacter
  • MLST
  • Recombination rate
  • Recombination tract length

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