Anti-VP6 IgG antibodies against group A and group C rotaviruses in South India

I. Mukhopadhya, D. Anbu, M. Iturriza-Gomara, J. J. Gray, David Brown, O. Kavanagh, M. K. Estes, G. Kang

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12 Citations (Scopus)

Abstract

In an epidemiological survey from South India, 936 serum samples were tested for IgG against recombinant baculovirus-expressed VP6 proteins from human group A and group C rotaviruses. The overall seroprevalence for group A was 100% and for group C was 2532% (95% CI 2264-2821). The lowest seroprevalence for group C was in children aged <10 years (1679%). An age-related rise in seroprevalence in group C, but not group A, suggests different patterns of exposure. Seroprevalence was similar in rural and urban subjects, unlike the higher prevalence in rural subjects in studies elsewhere.

Original languageEnglish
Pages (from-to)442-447
Number of pages6
JournalEpidemiology and Infection
Volume138
Issue number3
DOIs
Publication statusPublished - Mar 2010

Keywords

  • Gastrointestinal infections
  • Infectious disease epidemiology
  • Rotavirus
  • Serology

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