Association between hypermutator phenotype, clinical variables, mucoid phenotype, and antimicrobial resistance in Pseudomonas aeruginosa

David J. Waine, David Honeybourne, E. Grace Smith, Joanna L. Whitehouse, Chris G. Dowson

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

The presence of hypermutator Pseudomonas aeruginosa was associated with poorer lung function in patients at the Adult West Midlands CF Unit. Mucoid isolates were more likely to be hypermutators. The presence of resistant mutant subpopulations was associated with hypermutator phenotype but was not good enough to be used as a test for this phenotype.

Original languageEnglish
Pages (from-to)3491-3493
Number of pages3
JournalJournal of Clinical Microbiology
Volume46
Issue number10
DOIs
Publication statusPublished - Oct 2008
Externally publishedYes

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