Characterisation of small double stranded RNA molecule in Cryptosporidium hominis, Cryptosporidium felis and Cryptosporidium meleagridis

Francesca Leoni, Christopher Gallimore, Jonathan Green, James McLauchlin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Coding regions of double stranded RNA molecules from 3 human faecal samples containing Cryptosporidium hominis, C. felis and C. meleagridis were characterised by sequencing and compared with that previously obtained for C. parvum. Sequences outside the coding regions were also obtained. Overall similarities of between 86% and 92% and between 86% and 93% were observed in the nucleotide and amino acid sequences respectively between these species. These larger sequences will allow further molecular tools for detection, identification and characterisation of Cryptosporidium spp.

Original languageEnglish
Pages (from-to)299-306
Number of pages8
JournalParasitology International
Volume55
Issue number4
DOIs
Publication statusPublished - Dec 2006

Bibliographical note

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

Keywords

  • Cryptosporidium
  • RACE
  • Reverse transcription-polymerase chain reaction
  • dsRNA

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