Comparison of predicted with observed biokinetics of inhaled plutonium nitrate and gadolinium oxide in humans

Alan Hodgson, A. L. Shutt, George Etherington, S. A. Hodgson, E. Rance, G. N. Stradling, M. J. Youngman, A. Ziesenis, W. G. Kreyling

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

The absorption kinetics to blood of plutonium and gadolinium after inhalation as nitrate and oxide in humans and animals has been studied. For each material, values describing the time dependence of absorption were derived from the studies in animals and used with the ICRP human respiratory tract model to predict lung retention and cumulative amounts to blood for the volunteers inhaling the same materials. Comparison with the observed behaviour in the volunteers suggests that absorption of plutonium and gadolinium is reasonably species independent, and that data obtained from animal studies can be used to assess their biokinetic behaviour in humans.

Original languageEnglish
Pages (from-to)91-94
Number of pages4
JournalRadiation Protection Dosimetry
Volume105
Issue number1-4
DOIs
Publication statusPublished - 2003

Fingerprint

Dive into the research topics of 'Comparison of predicted with observed biokinetics of inhaled plutonium nitrate and gadolinium oxide in humans'. Together they form a unique fingerprint.

Cite this