Particle deposition in, and clearance from, the human nasal passage investigations are under way and will last for three years. Monodisperse particles ranging from 0.6 to greater than 30 μm are inhaled under three different breathing regimes; sitting and light exercise as defined in ICRP Publication 66, and controlled breathing. Deposition in the nasal passages are measured and clearance followed up for several days from the end of a single acute inhalation. Nose blow samples will be measured to study the assumption in ICRP Publication 66 that all clearance from the anterior region of the nose is intrinsic. Furthermore, the extent of inter-subject variation will be determined.
|Journal||Journal of Aerosol Science|
|Issue number||Suppl 1|
|Publication status||Published - 1996|
|Event||Proceedings of the 1996 European Aerosol Conference - Delft, Neth|
Duration: 9 Sep 1996 → 12 Sep 1996