Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in aminimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.
Bibliographical notePublisher Copyright:
© The Author 2016. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.
Copyright 2018 Elsevier B.V., All rights reserved.
- Ebola vaccine
- Oral fluid