Epidemic of Pseudomonas cepacia in an adult cystic fibrosis unit: Evidence of person-to-person transmission

D. L. Smith*, L. B. Gumery, E. G. Smith, D. E. Stableforth, M. E. Kaufmann, T. L. Pitt

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

83 Citations (Scopus)

Abstract

An epidemic of Pseudomonas cepacia occurred in an adult cystic fibrosis center in the United Kingdom, despite a policy of segregation of infected and noninfected patients within the hospital. Investigation of the outbreak by ribotyping and pulsed-field gel electrophoresis to characterize P. cepacia strain genomes together with inquiry into social contacts between patients revealed evidence of person-to-person transmission outside the hospital environment. Segregation policies aimed at reducing the spread of this infection in the cystic fibrosis community need to encompass patient contacts outside the hospital environment.

Original languageEnglish
Pages (from-to)3017-3022
Number of pages6
JournalJournal of Clinical Microbiology
Volume31
Issue number11
DOIs
Publication statusPublished - 1993
Externally publishedYes

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