Epidemiologic and genetic characteristics of mumps viruses isolated in China from 1995 to 2010

Aili Cui, Zhen Zhu, Meng Chen, Huanying Zheng, Leng Liu, Yan Wang, Yan Ma, Changyin Wang, Xueqiang Fang, Ping Li, Ronghui Guan, Shuang Wang, Jianhui Zhou, Lei Zheng, Hui Gao, Zhengrong Ding, Liqun Li, Fang Bo, Zhaodan Sun, Zhenying ZhangDaxing Feng, Jilan He, Hui Chen, Li Jin, Paul A. Rota, Wenbo Xu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

The epidemiologic and genetic characteristics of mumps viruses detected in China from 1995 to 2010 were analyzed in this study. Mumps remains endemic in China with a high overall incidence rate. The incidence of mumps in Western China was higher than that in other regions of the country. Each year, most of mumps cases occurred between April and July, but a small peak also occurred in November and December. Mumps cases primarily affected the under 15. year old age group. Virologic data demonstrated that genotype F was the predominant circulating genotype throughout China for at least 15. years and no other genotype was detected between 1995 and 2010. Analysis of sequence data from the small hydrophobic (SH) gene indicated that multiple transmission chains of genotype F were found in various provinces of China, with no apparent chronologic and geographic restriction. This is the first report describing the epidemiology of mumps and genetic characterization of mumps viruses at the national level in China.

Original languageEnglish
Pages (from-to)384-390
Number of pages7
JournalInfection, Genetics and Evolution
Volume21
DOIs
Publication statusPublished - Jan 2014

Bibliographical note

Funding Information:
This work was partially supported by the National Natural Science Foundation of China (Project No. 81102170), the National Infectious Disease Surveillance Program of the Ministry of Science and Technology of the People’s Republic of China ( 2012ZX10004201-003 and 2013ZX10004202 ).

Keywords

  • Epidemiology
  • Genetic characteristics
  • Mumps virus

Fingerprint

Dive into the research topics of 'Epidemiologic and genetic characteristics of mumps viruses isolated in China from 1995 to 2010'. Together they form a unique fingerprint.

Cite this