Evaluation of the measles, mumps and rubella vaccination catch-up campaign in England in 2013

Benedetto Simone, Uthayasoori Balasegaram, Maya Gobin, Charlotte Anderson, Andre Charlett, Louise Coole, Helen Maguire, Thomas Nichols, Chas Rawlings, Mary Ramsay, Maria Oliver

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

In January-March 2013 in England, confirmed measles cases increased in children aged 10-16 years. In April-September 2013, the National Health System and Public Health England launched a national measles-mumps-rubella (MMR) campaign based on data from Child Health Information Systems (CHIS) estimating that approximately 8% in this age group were unvaccinated. We estimated coverage at baseline, and, of those unvaccinated (target), the proportion vaccinated up to 20/08/2013 (mid-point) to inform further public health action.We selected a sample of 6644 children aged 10-16 years using multistage sampling from those reported unvaccinated in CHIS at baseline and validated their records against GP records. We adjusted the CHIS MMR vaccine coverage estimates correcting by the proportion of vaccinated children obtained through sample validation.We validated 5179/6644 (78%) of the sample records. Coverage at baseline was estimated as 94.7% (95% confidence intervals, CI: 93.5-96.0%), lower in London (86.9%, 95%CI: 83.0-90.9%) than outside (96.1%, 95%CI 95.5-96.8%). The campaign reached 10.8% (95%CI: 7.0-14.6%) of the target population, lower in London (7.1%, 95%CI: 4.9-9.3) than in the rest of England (11.4%, 95%CI: 7.0-15.9%). Coverage increased by 0.5% up to 95.3% (95% CI: 94.1-96.4%) but an estimated 210,000 10-16 year old children remained unvaccinated nationally.Baseline MMR coverage was higher than previously reported and was estimated to have reached the 95% campaign objective at midpoint. Eleven per cent of the target population were vaccinated during the campaign, and may be underestimated, especially in London. No further national campaigns are needed but targeted local vaccination activities should be considered.

Original languageEnglish
Pages (from-to)4681-4688
Number of pages8
JournalVaccine
Volume32
Issue number36
DOIs
Publication statusPublished - 6 Aug 2014

Keywords

  • England
  • Evaluation
  • Health campaigns
  • Measles-mumps-rubella vaccine
  • Vaccination

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