Existing medications among non-pregnancy-related listeriosis patients in England, 2007-2009

Piers Mook*, J. M. Jenkins, S. J. O'Brien, I. A. Gillespie

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)

Abstract

SUMMARY To identify which medications were most commonly taken by non-pregnancy-related listeriosis patients prior to illness, we compared the medications reported by 512 cases identified via national surveillance in England between 2007 and 2009 with national prescription data, using British National Formulary (BNF) coding. Relative risks and corresponding confidence intervals were calculated, as appropriate, for BNF chapters and sections. Among listeriosis cases, the rates for cytotoxic drugs, drugs affecting the immune response and corticosteroids were significantly higher than for other medications. However, interactions between medications and how medications might confound or be confounded by concurrent medical conditions need to be investigated further. Nevertheless our findings suggest that targeting food-safety advice to prevent this foodborne disease in certain treatment groups is warranted.

Original languageEnglish
Pages (from-to)36-44
Number of pages9
JournalEpidemiology and Infection
Volume141
Issue number1
DOIs
Publication statusPublished - Jan 2013

Keywords

  • British National Formulary
  • epidemiology
  • Listeria monocytogenes
  • listeriosis
  • medications
  • surveillance

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