Fetal growth, stillbirth, infant mortality and other birth outcomes near UK municipal waste incinerators; retrospective population based cohort and case-control study

Rebecca E. Ghosh, Anna Freni-Sterrantino, Philippa Douglas, Brandon Parkes, Daniela Fecht, Kees de Hoogh, Gary Fuller, John Gulliver, Anna Font, Rachel B. Smith, Marta Blangiardo, Paul Elliott*, Mireille B. Toledano, Anna L. Hansell

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Background: Some studies have reported associations between municipal waste incinerator (MWI) exposures and adverse birth outcomes but there are few studies of modern MWIs operating to current European Union (EU) Industrial Emissions Directive standards. Methods: Associations between modelled ground-level particulate matter ≤10 μm in diameter (PM10) from MWI emissions (as a proxy for MWI emissions) within 10 km of each MWI, and selected birth and infant mortality outcomes were examined for all 22 MWIs operating in Great Britain 2003–10. We also investigated associations with proximity of residence to a MWI. Outcomes used were term birth weight, small for gestational age (SGA) at term, stillbirth, neonatal, post-neonatal and infant mortality, multiple births, sex ratio and preterm delivery sourced from national registration data from the Office for National Statistics. Analyses were adjusted for relevant confounders including year of birth, sex, season of birth, maternal age, deprivation, ethnicity and area characteristics and random effect terms were included in the models to allow for differences in baseline rates between areas and in incinerator feedstock. Results: Analyses included 1,025,064 births and 18,694 infant deaths. There was no excess risk in relation to any of the outcomes investigated during pregnancy or early life of either mean modelled MWI PM10 or proximity to an MWI. Conclusions: We found no evidence that exposure to PM10 from, or living near to, an MWI operating to current EU standards was associated with harm for any of the outcomes investigated. Results should be generalisable to other MWIs operating to similar standards.

Original languageEnglish
Pages (from-to)151-158
Number of pages8
JournalEnvironment International
Volume122
DOIs
Publication statusPublished - Jan 2019
Externally publishedYes

Bibliographical note

Funding Information:
The study is funded by Public Health England (PHE), the Scottish government, the MRC-PHE Centre for Environment and Health and the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Health Impact of Environmental Hazards at King's College London and Imperial College London (HPRU-2012-10141) in partnership with Public Health England (PHE). The work of the UK Small Area Health Statistics Unit is funded by Public Health England as part of the MRC-PHE Centre for Environment and Health, funded also by the UK Medical Research Council (MR/L01341X/1). Danielle C Ashworth was funded by a MRC PhD studentship. PE is director of the MRC-PHE Centre for Environment and Health and acknowledges support from the NIHR Imperial Biomedical Research Centre. PE is associate director of Health Data Research UK-London. The funders had no role in study design, analyses, interpretation of the data, or decision to submit results.

Funding Information:
The study is funded by Public Health England (PHE), the Scottish government , the MRC-PHE Centre for Environment and Health and the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Health Impact of Environmental Hazards at King's College London and Imperial College London ( HPRU-2012-10141 ) in partnership with Public Health England (PHE). The work of the UK Small Area Health Statistics Unit is funded by Public Health England as part of the MRC-PHE Centre for Environment and Health, funded also by the UK Medical Research Council (MR/L01341X/1). Danielle C Ashworth was funded by a MRC PhD studentship. PE is director of the MRC-PHE Centre for Environment and Health and acknowledges support from the NIHR Imperial Biomedical Research Centre. PE is associate director of Health Data Research UK-London. The funders had no role in study design, analyses, interpretation of the data, or decision to submit results.

Publisher Copyright:
© 2018

Keywords

  • Birth weight
  • Environment
  • Epidemiology
  • Infant mortality
  • Municipal Waste Incinerator
  • Stillbirth

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