Infection with hepatitis C virus genotype 3 - Experience of a tertiary health care centre in south India

J. David, A. Rajasekar, H. D.D. Daniel, Siew Lin Ngui, B. Ramakrishna, U. G. Zachariah, C. E. Eapen, P. Abraham*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

To analyse the response rate and the predictive values of virological, biochemical and histological factors on HCV antiviral therapy in HCV genotype 3 infected patients, we retrospectively studied 21 HCV genotype 3 infected patients, who underwent HCV antiviral therapy. Low (57%) sustained viral response (SVR) rate and significant association of SVR with normalization of alanine transaminase (ALT) levels were observed in our study. Absence of early viral response (EVR) showed high (80%) predictive value on SVR. Absence of EVR and normalisation of the ALT levels can predict the outcome of HCV antiviral therapy.

Original languageEnglish
Pages (from-to)155-157
Number of pages3
JournalIndian Journal of Medical Microbiology
Volume28
Issue number2
DOIs
Publication statusPublished - 1 Apr 2010

Keywords

  • Early viral response
  • Pegylated interferon
  • Ribavirin
  • Standard interferon
  • Sustained viral response

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