Klebsiella pneumoniae producing KPC carbapenemase in a district general hospital in the UK

N. Virgincar, S. Iyer, A. Stacey, S. Maharjan, Rachel Pike, C. Perry, J. Wyeth, Neil Woodford

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

We report two patients with multidrug-resistant KPC-carbapenemase-producing Klebsiella pneumoniae urinary tract infections. A blaKPC-2 gene was detected in both of the isolates by polymerase chain reaction and sequencing. The isolates had identical pulsed-field gel electrophoresis patterns and belonged to sequence type ST11. The index patient probably acquired the KPC-producing strain while in hospital in Curaçao, with subsequent nosocomial transmission to the second patient occurring in our hospital. We describe the interventions that were taken to prevent its further spread within the acute Trust and the community.

Original languageEnglish
Pages (from-to)293-296
Number of pages4
JournalJournal of Hospital Infection
Volume78
Issue number4
DOIs
Publication statusPublished - Aug 2011

Keywords

  • Klebsiella pneumoniae
  • KPC carbapenemase
  • Polymerase chain reaction

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