Million migrants study of healthcare and mortality outcomes in non-eu migrants and refugees to england: Analysis protocol for a linked population-based cohort study of 1.5 million migrants [version 1; referees: 2 approved, 2 approved with reservations]

Rachel Burns, Neha Pathak, Ines Campos-Matos, Dominik Zenner, Srinivasa Vittal Katikireddi, Morris C. Muzyamba, J. Jaime Miranda, Ruth Gilbert, Harry Rutter, Lucy Jones, Elizabeth Williamson, Andrew C. Hayward, Liam Smeeth, Ibrahim Abubakar, Harry Hemingway, Robert W. Aldridge*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Background: In 2017, 15.6% of the people living in England were born abroad, yet we have a limited understanding of their use of health services and subsequent health conditions. This linked population-based cohort study aims to describe the hospital-based healthcare and mortality outcomes of 1.5 million non-European Union (EU) migrants and refugees in England. Methods and analysis: We will link four data sources: first, non-EU migrant tuberculosis pre-entry screening data; second, refugee pre-entry health assessment data; third, national hospital episode statistics; and fourth, Office of National Statistics death records. Using this linked dataset, we will then generate a population-based cohort to examine hospital-based events and mortality outcomes in England between Jan 1, 2006, and Dec 31, 2017. We will compare outcomes across three groups in our analyses: 1) non-EU international migrants, 2) refugees, and 3) general population of England. Ethics and dissemination: We will obtain approval to use unconsented patient identifiable data from the Secretary of State for Health through the Confidentiality Advisory Group and the National Health Service Research Ethics Committee. After data linkage, we will destroy identifying data and undertake all analyses using the pseudonymised dataset. The results will provide policy makers and civil society with detailed information about the health needs of non-EU international migrants and refugees in England.

Original languageEnglish
Article number4
JournalWellcome Open Research
Volume4
DOIs
Publication statusPublished - 2019

Bibliographical note

Funding Information:
RWA is supported by a Wellcome Trust Clinical Research Career Development Fellowship (206602/Z/17/Z). NP is funded by a UCL Wellcome Trust Clinical Research Training Fellowship (211162/Z/18/Z). ACHamp;#x2019;s salary is provided by Central and North West London NHSCommunity Trust. AS is funded by UCLH Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the NHS, the Wellcome Trust, the NIHR or the Department of Health, International Organisation for Migration or Public Health England. SVK acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC_UU_12017/13 amp; MC_UU_12017/15) and the Scottish Government Chief Scientist Office (SPHSU13 amp; SPHSU15). HH is a National Institute for Health Research (NIHR) Senior Investigator. His work is supported by: Health Data Research UK, which is funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, Department of Health and Social Care (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), British Heart Foundation and Wellcome Trust. The BigData@Heart Consortium, funded by the Innovative Medicines Initiative-2 Joint Undertaking under grant agreement No. 116074. This Joint Undertaking receives support from the European Union ’s Horizon 2020 research and innovation programme and EFPIA; it is chaired, by DE Grobbee and SD Anker, partnering with 20 academic and industry partners and ESC. The National Institute for Health Research University College London Hospitals Biomedical Research Centre. JJM acknowledges having received support from the Alliance for Health Policy and Systems Research (HQHSR1206660), DFID/MRC/Wellcome Global Health Trials (MR/M007405/1), Fogarty International Center (R21TW009982, D71TW010877), Grand Challenges Canada (0335-04), International Development Research Center Canada (106887, 108167), Inter-American Institute for Global Change Research (IAI CRN3036), Medical Research Council (MR/P008984/1, MR/P024408/1, MR/P02386X/1), National Cancer Institute (1P20CA217231), National Heart, Lung and Blood Institute (HHSN268200900033C, 5U01HL114180, 1UM1HL134590), National Institute of Mental Health (1U19MH098780), Swiss National Science Foundation (40P740-160366), Wellcome Trust (074833/Z/04/Z, 093541/Z/10/Z, 107435/Z/15/Z, 103994/Z/14/Z, 205177/Z/16/Z) and the World Diabetes Foundation (WDF15-1224). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Funding Information:
a UCL Wellcome Trust Clinical Research Training Fellowship (211162/Z/18/Z). ACH’s salary is provided by Central and North West London NHS Community Trust. AS is funded by UCLH Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the NHS, the Wellcome Trust, the NIHR or the Department of Health, International Organisation for Migration or Public Health England. SVK acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC 栀UU 栂b2017/13 & MC 栀UU 栂b2017/15) and the Scottish Government Chief Scientist Office (SPHSU13 & SPHSU15). HH is a National Institute for Health Research (NIHR) Senior Investigator. His work is supported by: Health Data Research UK, which is funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, Department of Health and Social Care (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), British Heart Foundation and Wellcome Trust. The BigData@Heart Consortium, funded by the Innovative Medicines Initiative-2 Joint Undertaking under grant agreement No. 116074. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA; it is chaired, by DE Grobbee and SD Anker, partnering with 20 academic and industry partners and ESC. The National Institute for Health Research University College London Hospitals Biomedical Research Centre. JJM acknowledges having received support from the Alliance for Health Policy and Systems Research (HQHSR1206660), DFID/MRC/Wellcome Global Health Trials (MR/M007405/1), Fogarty International Center (R21TW009982, D71TW010877), Grand Challenges Canada (0335-04), International Development Research Center Canada (106887, 108167), Inter-American Institute for Global Change Research (IAI CRN3036), Medical Research Council (MR/P008984/1, MR/P024408/1, MR/P02386X/1), National Cancer Institute (1P20CA217231), National Heart, Lung and Blood Institute (HHSN268200900033C, 5U01HL114180, 1UM1HL134590), National Institute of Mental Health (1U19MH098780), Swiss National Science Foundation (40P740-160366), Wellcome Trust (074833/Z/04/Z, 093541/Z/10/Z, 107435/Z/15/Z, 103994/Z/14/Z, 205177/Z/16/Z) and the World Diabetes Foundation (WDF15-1224).

Funding Information:
RWA is supported by a Wellcome Trust Clinical Research Career Development Fellowship (206602/Z/17/Z). NP is funded by a UCL Wellcome Trust Clinical Research Training Fellowship (211162/Z/18/Z). ACH’s salary is provided by Central and North West London NHS Community Trust. AS is funded by UCLH Foundation Trust. The views expressed are those of the author(s) and not necessarily those of the NHS, the Wellcome Trust, the NIHR or the Department of Health, International Organisation for Migration or Public Health England. SVK acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC_UU_12017/13 & MC_UU_12017/15) and the Scottish Government Chief Scientist Office (SPHSU13 & SPHSU15). HH is a National Institute for Health Research (NIHR) Senior Investigator. His work is supported by: Health Data Research UK, which is funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, Department of Health and Social Care (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), British Heart Foundation and Wellcome Trust. The BigData@Heart Consortium, funded by the Innovative Medicines Initiative-2 Joint Undertaking under grant agreement No. 116074. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA; it is chaired, by DE Grobbee and SD Anker, partnering with 20 academic and industry partners and ESC. The National Institute for Health Research University College London Hospitals Biomedical Research Centre. JJM acknowledges having received support from the Alliance for Health Policy and Systems Research (HQHSR1206660), DFID/MRC/Wellcome Global Health Trials (MR/M007405/1), Fogarty International Center (R21TW009982, D71TW010877), Grand Challenges Canada (0335-04), International Development Research Center Canada (106887, 108167), Inter-American Institute for Global Change Research (IAI CRN3036), Medical Research Council (MR/P008984/1, MR/P024408/1, MR/ P02386X/1), National Cancer Institute (1P20CA217231), National Heart, Lung and Blood Institute (HHSN268200900033C, 5U01HL114180, 1UM1HL134590), National Institute of Mental Health (1U19MH098780), Swiss National Science Foundation (40P740-160366), Wellcome Trust (074833/Z/04/Z, 093541/Z/10/Z, 107435/Z/15/Z, 103994/Z/14/Z, 205177/Z/16/Z) and the World Diabetes Foundation (WDF15-1224).

Publisher Copyright:
© 2019 Burns R et al.

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

Keywords

  • Health
  • Healthcare
  • Migrant
  • Migration
  • Mortality
  • Refugee

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