Mycobacterium abscessus infection in cystic fibrosis: Molecular typing and clinical outcomes

Kathryn A. Harris, Dervla Kenna

Research output: Contribution to journalReview articlepeer-review

18 Citations (Scopus)

Abstract

Mycobacterium abscessusis a significant pathogen in the cystic fibrosis patient population. PCR amplification and sequencing can provide accurate subspecies identification, and can predict macrolide susceptibility, which is becoming increasingly important for patient management. Molecular techniques for further typing of isolates provide tools for the ongoing investigations into the clinical impact of particular M. abscessusstrains. Whole-genome sequencing is likely to be the only technique that provides sufficient resolution for investigating transmission events between patients.

Original languageEnglish
Pages (from-to)1241-1246
Number of pages6
JournalJournal of Medical Microbiology
Volume63
DOIs
Publication statusPublished - 1 Oct 2014

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