Poly-γ-D-glutamic acid capsule interferes with lytic infection of Bacillus anthracis by B. anthracis-specific bacteriophages

David Negus, Jane Burton, Angela Sweed, Romuald Gryko, Peter W. Taylor

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

The poly-γ-D-glutamic acid capsule of Bacillus anthracis is a barrier to infection by B. anthracis-specific bacteriophages. Capsule expression was found to completely inhibit lytic infection by γ phage, an observation supported by the demonstration that this phage does not elaborate a hydrolase that would facilitate penetration through the protective capsule outer layer

Original languageEnglish
Pages (from-to)714-717
Number of pages4
JournalApplied and Environmental Microbiology
Volume79
Issue number2
DOIs
Publication statusPublished - Jan 2013

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