Real-time PCR for detection of the O25b-ST131 clone of Escherichia coli and its CTX-M-15-like extended-spectrum β-lactamases

Hiran Dhanji*, Michel Doumith, Olivier Clermont, Erick Denamur, Russell Hope, David Livermore, Neil Woodford

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

CTX-M-15 has become the most prevalent extended-spectrum β-lactamase amongst Escherichia coli in many countries during the past decade. Its dominance partly reflects the dissemination of an E. coli O25b:H4 ST131 clone that commonly produces this enzyme. We describe rapid real-time polymerase chain reaction (PCR) assays able to detect E. coli belonging to the ST131 clone and to identify blaCTX-M-15-like.

Original languageEnglish
Pages (from-to)355-358
Number of pages4
JournalInternational Journal of Antimicrobial Agents
Volume36
Issue number4
DOIs
Publication statusPublished - Oct 2010

Keywords

  • ESBL
  • Epidemic
  • Escherichia coli
  • LightCycler PCR
  • Pandemic clone

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