Reconstruction of doses from ionizing radiation using fluorescence in situ hybridization techniques

Alan Edwards, M. Szłuińska, David C. Lloyd

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

This paper reviews cytogenetic methods of biological dosimetry. The most reliable indicator of exposure to ionizing radiation is the observation of dicentrics in human peripheral lymphocytes. The major disadvantage is that dicentrics cannot be used for exposures that occur many years prior to blood sampling. In such cases, translocations are the aberrations of choice, and recent developments in their measurement using fluorescence in situ hybridization techniques are highlighted.

Original languageEnglish
Pages (from-to)S63-S67
JournalBritish Journal of Radiology
Volume80
Issue numberSPEC. ISS. 1
DOIs
Publication statusPublished - 2007

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