Regression of AIDS-related Kaposi's sarcoma during therapy with thalidomide

Rolf A. Solèr, Mark Howard, Nicola S. Brink, Diana Gibb, Richard Tedder, David Nadal*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

67 Citations (Scopus)

Abstract

A 14-year-old girl with HIV infection and subcutaneous Kaposi's sarcoma (KS) received thalidomide therapy for oral ulcers, resulting in regression of KS lesions, disappearance of KS-associated herpesvirus (KSHV) DNA from blood, and reduced viral load in tumor tissue. Administration of granulocyte colony- stimulating factor resulted in clinical exacerbation of KS add reappearance of KSHV DNA in blood.

Original languageEnglish
Pages (from-to)501-505
Number of pages5
JournalClinical Infectious Diseases
Volume23
Issue number3
DOIs
Publication statusPublished - 1996

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