Sarcoidosis presenting with an acute Guillain-Barré syndrome

Robert Miller*, Nicholas Sheron, Stephen Semple

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

38 Citations (Scopus)

Abstract

A 28 year old Caucasian male presented with an acute Guillain-Barré syndrome and bilateral facial weakness. He had an abnormal chest radiograph. Lumbar pucture revealed acellular fluid with a raised protein count and lung function tests showed a restrictive ventilatory defect. The patient deteriorated and required mechanical ventilation for 14 days. Steroids and plasmapheresis were not used and the patient spontaneously recovered. Two months after presentation limb power was almost normal but there was residual partial bilateral facial weakness. The chest radiograph remained abnormal and repeat lung function tests showed a persistent restrictive ventilatory defect and a reduced gas transfer coefficient. A transbronchial biopsy revealed non-caseating granulomata. The association between neurosarcoidosis and Guillain-Barré polyneuropathy is discussed and the literature reviewed.

Original languageEnglish
Pages (from-to)765-767
Number of pages3
JournalPostgraduate Medical Journal
Volume65
Issue number768
DOIs
Publication statusPublished - 1989
Externally publishedYes

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