Specificity of IS6110-based DNA fingerprinting and diagnostic techniques for Mycobacterium tuberculosis complex

Willie A. Githui, Stuart M. Wilson, Francis Drobniewski

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Restriction fragment length polymorphism and hybridization of DNA extracted from Mycobacterium tuberculosis, nontuberculous mycobacteria, and nonmycobacterial species with a probe derived from IS6110 confirmed that IS6110 was specific to M. tuberculosis complex. In addition, DNA amplification with IS6110-specific primers yielded a 181-bp fragment only in DNA from M. tuberculosis complex isolates.

Original languageEnglish
Pages (from-to)1224-1226
Number of pages3
JournalJournal of Clinical Microbiology
Volume37
Issue number4
DOIs
Publication statusPublished - 1999

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