The future of biological dosimetry in mass casualty radiation emergency response, personalized radiation risk estimation and space radiation protection

Elizabeth A. Ainsbury*, Jayne Moquet, Mingzhu Sun, Stephen Barnard, Michele Ellender, David Lloyd

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Purpose: The aim of this brief personal, high level review is to consider the state of the art for biological dosimetry for radiation routine and emergency response, and the potential future progress in this fascinating and active field. Four areas in which biomarkers may contribute to scientific advancement through improved dose and exposure characterization, as well as potential contributions to personalized risk estimation, are considered: emergency dosimetry, molecular epidemiology, personalized medical dosimetry, and space travel. Conclusion: Ionizing radiation biodosimetry is an exciting field which will continue to benefit from active networking and collaboration with the wider fields of radiation research and radiation emergency response to ensure effective, joined up approaches to triage; radiation epidemiology to assess long term, low dose, radiation risk; radiation protection of workers, optimization and justification of radiation for diagnosis or treatment of patients in clinical uses, and protection of individuals traveling to space.

Original languageEnglish
JournalInternational Journal of Radiation Biology
DOIs
Publication statusAccepted/In press - 2021

Bibliographical note

Funding Information:
The authors of this work have been partly supported by the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Chemical & Radiation Threats & Hazards, a partnership between PHE and Imperial College London. The views expressed are those of the authors and not necessarily those of the NIHR, PHE or the Department of Health and Social Care.

Publisher Copyright:
© Copyright © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.

Keywords

  • biological dosimetry
  • biomarkers of dose and risk
  • Radiation
  • space flight radiation

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