The importance of surveillance: Group W meningococcal disease outbreak response and control in England

Helen Campbell, Shamez Ladhani

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Invasive meningococcal disease (IMD) is associated with high morbidity and mortality. Recently, use of the quadrivalent MenACWY conjugate vaccines has increased with the emergence of a hypervirulent MenW:cc11 strain in certain parts of the world, especially South America. In England, MenW:cc11 IMD cases increased rapidly after 2009 and was responsible for 24% of all IMD cases in 2014/15 compared to < 5% previously, leading to the emergency introduction of a national teenage MenACWY conjugate vaccine programme in August 2015. Unusually, MenW:cc11 cases have been described presenting with severe gastrointestinal symptoms, including abdominal pain and diarrhoea, followed by rapid clinical deterioration and death.

Original languageEnglish
Pages (from-to)369-371
Number of pages3
JournalInternational Health
Volume8
Issue number6
DOIs
Publication statusPublished - Nov 2016

Keywords

  • Gastrointestinal symptoms
  • Group W meningococcal disease
  • Invasive meningococcal disease
  • MenACWY conjugate vaccination
  • Surveillance

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