The reactions of 1·0 nanometre diameter plutonium-238 dioxide particles with rat lung fluid

John Cooper*, G. N. Stradling, H. Smith, S. E. Breadmore

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    15 Citations (Scopus)

    Abstract

    The reactions of 1·0 nm particles of plutonium-238 dioxide with rat lung fluid have been studied both in vivo and in vitro. In both cases two products have been identified, (i) plutonium-labelled pulmonary surfactant and (ii) a heterogeneous plutonium-labelled material isolated by column chromatography. The formation of plutonium-labelled pulmonary surfactant results in the rapid translocation of plutonium from lungs to blood and in a high urinary excretion relative to administered plutonium citrate.

    Original languageEnglish
    Pages (from-to)453-466
    Number of pages14
    JournalInternational Journal of Radiation Biology
    Volume36
    Issue number5
    DOIs
    Publication statusPublished - 1979

    Fingerprint

    Dive into the research topics of 'The reactions of 1·0 nanometre diameter plutonium-238 dioxide particles with rat lung fluid'. Together they form a unique fingerprint.

    Cite this