Transverse myelitis caused by hepatitis E: Previously undescribed in adults

Pamela Sarkar, Catherine Morgan, Samreen Ijaz

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)


    We report the case of a 62-year-old Caucasian woman who was admitted with urinary retention and lower limb paraesthesia following a week's prodromal illness of headache and malaise. Liver function tests showed a picture of acute hepatocellular dysfunction. She developed reduced lower limb power, brisk reflexes, extensor plantars, a sensory level at T8 and reduced anal sphincter tone, establishing a clinical diagnosis of transverse myelitis. A spinal MRI showed no evidence of cauda equina or spinal cord compression. Cerebrospinal fluid (CSF) analysis showed raised protein and raised white cell count. Hepatitis E IgM and IgG were positive and hepatitis E virus was found in her CSF. She was treated with methylprednisolone and is slowly recovering with physiotherapy.

    Original languageEnglish
    JournalBMJ Case Reports
    Publication statusPublished - 6 Jul 2015


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