Two linked enteroinvasive Escherichia coli outbreaks, Nottingham, UK, June 2014

Sophie Newitt, Vanessa MacGregor, Vivienne Robbins, Laura Bayliss, Marie Anne Chattaway, Tim Dallman, Derren Ready, Heather Aird, Richard Puleston, Jeremy Hawker

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Enteroinvasive Escherichia coli (EIEC) outbreaks are uncommon in Europe. In June 2014, two EIEC outbreaks occurred in Nottingham, UK, within 2 days; outbreak A was linked to a takeaway restaurant and outbreak B to a wedding party. We conducted 2 analytical studies: a case-control study for outbreak A and a cohort study for outbreak B. We tested microbiological and environmental samples, including by using whole-genome sequencing. For both outbreaks combined, we identified 157 probable case-patients; 27 were laboratory-confirmed as EIEC O96:H19-positive. Combined epidemiologic, microbiological, and environmental findings implicated lettuce as the vehicle of infection in outbreak A, but the source of the organism remained unknown. Whole-genome sequencing identified the same organism in cases from both outbreaks, but no epidemiologic link was confirmed. These outbreaks highlight that EIEC has the capacity to cause large and severe gastrointestinal disease outbreaks and should be considered as a potential pathogen in foodborne outbreaks in Europe.

Original languageEnglish
Pages (from-to)1178-1184
Number of pages7
JournalEmerging Infectious Diseases
Volume22
Issue number7
DOIs
Publication statusPublished - Jul 2016

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