Wound botulism, its neurological manifestations, treatment and outcomes: A case series from the Glasgow outbreak, 2015

Sarah Jane Martin*, Gillian Penrice, Corinne Amar, Kathleen Grant, George H. Gorrie

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Background and aims: We examined the neurological manifestations, treatment and outcomes of a subset of 25 patients within the largest ever outbreak of wound botulism in Europe. Methods and results: All 25 cases were intravenous drug users. The most common presenting symptom was dysarthria in 19/25 (76%), followed by dysphagia in 12/25 (48%), blurred vision in 10/25 (40%) and double vision in 8/25 (32%). Microbiological analysis confirmed the diagnosis in nine cases (36%). Duration of admission positively correlated with time to antitoxin, time to wound debridement and female sex. Conclusion: As the outbreak continued, hospital stays shortened, reflecting growing awareness of the outbreak and quicker treatment initiation.

Original languageEnglish
Pages (from-to)136-141
Number of pages6
JournalScottish Medical Journal
Volume62
Issue number4
DOIs
Publication statusPublished - 1 Nov 2017

Bibliographical note

Publisher Copyright:
© The Author(s) 2017.

Keywords

  • Wound botulism
  • dysarthria
  • muscle-popping

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